Protein purification system
- Aseptic techniques
- Building the protein expression construct and properties of the host strain
- How microbes (and other cells) are able to churn out useful protein products
- Design of conventional stirred tank bioreactor and other bioreactors
- Hands-on operation of a bioreactor to grow cells and produce a protein
- Monitoring and controlling bioreactor parameters to consistently produce a quality product.
- Cleaning and sterilizing the bioreactor
- Downstream bioprocess and product purification by chromatography
- Current Good Manufacturing Practices for Biologics
- Good Documentation Practices and Standard Operating Procedures (SOPs)
- Quality assurance and Quality control of critical product attributes
- Biohazard handling, waste decontamination, and autoclaving
- Detailed topics and course schedule will be provided upon registration